Efficacy of endoscopic ligation with O-ring closure for preventing gastric post- endoscopic submucosal dissection bleeding under antithrombotic therapy: A prospective study

Efficacy of endoscopic ligation with O-ring closure for preventing gastric post- endoscopic submucosal dissection bleeding under antithrombotic therapy: A prospective study - Efficacy of E-LOC for preventing gastric post- endoscopic submucosal dissection bleeding

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000045906

Enrollment

Registered

2021-10-28

Start date

2019-08-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastric lesions

Interventions

Closure with E-LOC method

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The inclusion criteria were treatment by ESD for early gastric carcinoma or adenoma that could not be preoperatively distinguished from early gastric carcinoma based on the Japanese Gastroenterological Endoscopy Society (JGES) criteria, current therapy with at least one antithrombotic drug.

Exclusion criteria

Exclusion criteria: Pyloric ring or cardia lesion Lesion involving more than half-circumference of the stomach

Design outcomes

Primary

Measure	Time frame
The rate of post-ESD bleeding with E-LOC	—

Secondary

Measure	Time frame
Complete defect closure rate Procedure time for closure Sustained closure rate Complications after E-LOC	—

Countries

Japan

Contacts

Public ContactNORIKO NISHIYAMA

Faculty of Medicine, Kagawa University Department of Gastroenterology and Neurology

nishiyama.noriko@kagawa-u.ac.jp0878985111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026