Healthy adults
Conditions
Interventions
Applying a test product on the face twice a day for 6 weeks.
Sponsors
KOBAYASHI Pharmaceutical Co., Ltd.
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Aged more than 30 to less than 60 years old. 2. Japanese female 3. Persons who are aware that they have two or more unraised spots on their cheeks 4. Persons who are confirmed to have two or more senile pigmented spots on their cheeks at the time of screening examination. 5. Persons who do not plan to get heavily suntanned or sunburned during the test period. 6. Persons who use "sunscreen" or "sun protection cosmetics" on a daily basis and are able to use them during the test period. 7. Persons who will be exposed to the sun for less than 4 hours on workdays. 8. Persons who can agree to participate in the study voluntarily in writing.
Exclusion criteria
Exclusion criteria: 1. Persons who have scratches or eczema on their face. 2. Persons who have experienced medical cosmetic treatment or are planning during the test period. 3. Persons who have experienced special skincare treatments (beauty salons, esthetic treatments, etc.) within the past 4 weeks or are planning during the test period. 4. Persons who use cosmetics containing whitening ingredients or take medicine or supplements claiming whitening function. 5. Persons who have changed or newly started using supplements, facial cosmetics or sunscreens within the past 4 weeks. 6. Those who have been exposed to UV radiation beyond their daily lives within the last 4 weeks or will be exposed during the test period. 7. Persons who work night shifts or day and night shifts. 8. Persons who are being treated at a medical institution for the treatment or prevention of illness, or those who are judged to be in need of treatment. 9. Persons who have a critical illness related to glucose metabolism, lipid metabolism, liver function, renal function, cardiovascular system, respiratory tract, endocrine system, immune system or nervous system, or have an anamnestic history of psychiatric disorder. 10. Persons with a history of alcohol and drug addiction 11. Persons who may develop allergies to cosmetics and foods 12. Persons who are pregnant, lactating, or wish to become pregnant during the study period 13. Persons who have participated in other human studies within the last 4 weeks, or who are planning to participate in other human studies during the study period. 14. Persons who are overly tanned. 15. Persons who are currently using cream-type skincare products. 16. Persons who work for a cosmetics company or have a family member living with them who works for a cosmetics company. 17. Persons who are judged as unsuitable for the study by the investigator (or the person responsible for this study).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of the number of pigmented spots, the skin brightness or melanin amount after continuous use of a test product for 3, 6 weeks. | — |
Countries
Japan
Contacts
Public ContactKazumi Naganuma
DRC CO., Ltd. Product testing Department
Outcome results
None listed