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Study on Health Promotion by Shinrin-yoku - Effects of Shinrin-yoku on Immune System and Relationship with Endocrine System

Effects of Shinrin-yoku on mucosal immunity: Randomized controlled study - Changes in mucosal immune function by Shinrin-yoku: Randomized Controlled Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000045851
Enrollment
80
Registered
2021-10-25
Start date
2021-09-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy person

Interventions

Two and a half hours of Shinrin-yoku, including a 60-minute walk (spend time in the forest using all five senses while taking a slow stroll). The control group will perform the same activity in the c

Sponsors

National Hospital Organization (Tokyo Medical Center Clinical Research Center)
Lead Sponsor
Tokyo Women&#39
Collaborator
s Medical University Tokyo Medical University
Collaborator

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: No difficulty walking for about 90 minutes. The participants live in an urban area in the Kanto region and are able to travel to Ginza and Musashi Itsukaichi Station on their own without difficulty.

Exclusion criteria

Exclusion criteria: Those who are taking drugs such as antibiotics, anti-inflammatory drugs, anti-allergic drugs, steroids, immunosuppressive drugs, etc., which may affect this study. Those who have related diseases (collagen diseases, common cold, inflammatory diseases, etc.), and those who currently have a smoking habit.

Design outcomes

Primary

MeasureTime frame
Changes in sIgA levels after 2.5 hours of Shinrin-yoku, including 60 minutes of walking

Secondary

MeasureTime frame
Changes in NK cell activity, cytokines such as IgG and CD-8, and stress hormones such as cortisol before and after 2.5 hours of Shinrin-yoku, including 60 minutes of walking in the forest and city

Countries

Japan

Contacts

Public ContactHiroko Ochiai

National Hospital Organization Tokyo Medical Center Department of Plastic and Reconstructive Surgery

ochiroko@gmail.com0334110111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026