Effectiveness of measuring salivary alpha-amylase activity to evaluate surgical stimulus and post operative pain in patients undergoing breast surgery

Effectiveness of measuring salivary alpha-amylase activity to evaluate surgical stimulus in patients undergoing breast surgery - Effectiveness of measuring salivary alpha-amylase activity to evaluate surgical stimulus and post operative pain

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000045845

Enrollment

Registered

2021-10-29

Start date

2011-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients scheduled for breast surgery

Interventions

administration dose of fentanyl during anesthesia induction (1.0 mcg/kg) administration dose of fentanyl during anesthesia induction (2.0 mcg/kg)

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists (ASA) physical status 1

Exclusion criteria

Exclusion criteria: salivary secretion disorder

Design outcomes

Primary

Measure	Time frame
Values of salivary alpha-amylase activity before and after tracheal intubation under general anesthesia.	—

Secondary

Measure	Time frame
Relationship between intraoperative salivary alpha-amylase activity level and post operative analgesic consumption	—

Countries

Japan

Contacts

Public ContactNoriya Hirose

Nihon University School of Medicine Department of Anesthesiology

hirose.noriya@nihon-u.ac.jp0339728111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026