Biological Psychiatry Study in Depressive Symptoms Associated with Heart Failure

Biological Psychiatry Study in Depressive Symptoms Associated with Heart Failure - Biological Psychiatry Study in Depressive Symptoms Associated with Heart Failure

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000045819

Enrollment

Registered

2022-05-01

Start date

2021-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression, Heart Failure

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Those who are 20 years of age or older at the time of obtaining consent 2) A person who, after receiving sufficient explanation and understanding, has given written consent of his or her own free will to participate in this research

Exclusion criteria

Exclusion criteria: 1) Patients with serious (systemic or local) infections 2) Patients who are considered to be easily infected due to serious underlying diseases or reduced immunocompetence 3) Patients with severe cognitive impairment 4) Other patients who are judged by the principal investigator to be inappropriate as research subjects

Design outcomes

Primary

Measure	Time frame
Correlation between PHQ-9 scores and blood levels of various substances (tryptophan, kynurenine, kynurenic acid, quinolinic acid) and various (CIDEC, RNASE1, SLC36A1, STYXL1) mRNA expression levels	—

Secondary

Measure	Time frame
1) Correlation between PHQ-9 score and severity of heart failure 2) Correlation between PHQ-9 score and duration of heart failure	—

Countries

Japan

Contacts

Public ContactTomoyuki Isoyama

Hokkaido University Department of psychiatry, graduate school of medical science

tgo82301@elms.hokudai.ac.jp011-706-5160

Outcome results