healthy individuals
Conditions
Interventions
HCl 100ml single time 10minutes
Sponsors
Hyogo College of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 20 to 80 years old Those who do not have significant subjective symptoms. Taking gastrointestinal motility improver, gastric acid secretion inhibitor (H2 receptor antagonist, proton pump inhibitor), gastric mucosa protectant, prostaglandin preparation, antidepressant, anxiolytic, sleep inducer, antipsychotic Those who have not. A person who understands the contents of this research and obtains written consent to participate in the research.
Exclusion criteria
Exclusion criteria: Those who are clearly having diseases that cause upper abdominal gastrointestinal symptoms such as malignant tumors, peptic ulcers, heart diseases, systemic diseases (neurological diseases such as Parkinson's disease and metabolic diseases such as diabetes). Persons with clear causes of upper abdominal gastrointestinal symptoms such as overdrinking, overeating, taking NSAIDs, and extremely strong stress. Persons with a history of upper gastrointestinal surgery such as stomach and esophagus. Persons with severe liver dysfunction and renal dysfunction. Pregnant women, lactating women, or those who wish to become pregnant during the period of participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rectum initial perception threshold rectum pain threshold | — |
Countries
Japan
Contacts
Public ContactToshihiko Tomita
Dr. Division of Gastroenterology,Department of Internal Medicine
Outcome results
None listed