Repeated implantation failure, repeated pregnancy loss, chronic endometritis
Conditions
Interventions
Suggest EMMA/ALICE test and perform the same for patients who requested the tests
Explain the results to the study participants based on the test result reports, and validate subsequent tests and add
Sponsors
Kamiya ladies clinic
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1,Repeated implantation failure with no clinical pregnancy after two or more implantations. 2,Repeated miscarriages (two or more previous miscarriages) 3,Patients with difficult-to-treat cases of bacterial vaginosis 4, Patients suspected of having chronic endometritis by the hysteroscopy
Exclusion criteria
Exclusion criteria: Untreated Fallopian Tube Hydrops. Intrauterine lesions (endometrial polyps, submucosal fibroids, etc.) The patient has received antibiotics 3 months prior to the test. Have a serious medical condition.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ongoing pregnancy rate; Comparison of ongoing pregnancy rates between the normal uterine microbiota group and the treatment intervention group (after treatment intervention for Lactobacillus <90%) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1,Detection of the percentage of patients with recurrent implantation failure, recurrent miscarriages, and patients suspected of CE by other tests whose intrauterine flora is actually dominated by pathogenic bacteria other than Lactobacillus species. 2,Impact on implantation rate and clinical pregnancy rate in patients with recurrent implantation failure and recurrent miscarriage after this test 3,Verify the concordance rate with vaginal culture and hysteroscopy. 4,Frequency of complications from the test such as pain, infection, uterine perforation, and vagus reflex | — |
Countries
Japan
Contacts
Public ContactNanako Iwami
Kaimiya ladies clinic Reproductive health
Outcome results
None listed