Examination of the effectiveness of low-molecular-weight lychee polyphenol-containing foods for tinnitus and ear discomfort in healthy subjects

Examination of the effectiveness of low-molecular-weight lychee polyphenol-containing foods for tinnitus and ear discomfort in healthy subjects: a randomized, double blind, placebo-controlled study - Examination of the effectiveness of low-molecular-weight lychee polyphenol-containing foods for tinnitus and ear discomfort in healthy subjects

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000045724

Enrollment

Registered

2021-10-14

Start date

2021-10-14

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adult

Interventions

Take the test article for 8 weeks Take the placebo for 8 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Subjects who realize mild tinnitus 2. Subjects with high THI scores 3. Subjects recognized as healthy by a doctor's diagnosis

Exclusion criteria

Exclusion criteria: 1. Subjects receiving treatment, medication, and lifestyle guidance from a doctor due to tinnitus or ear disease 2. Subjects who underwent ear surgery 3. Subjects using hearing aids and other hearing aids 4. Pregnant women, lactating women, and those who are planning to become pregnant during the test period 5. Subjects who are judged as unsuitable for the study by the investigator for the other reason

Design outcomes

Primary

Measure	Time frame
THI questionnaire, Pitch Match Test, Audiometry	—

Secondary

Measure	Time frame
Subjective assessment, VAS, Blood test	—

Countries

Japan

Contacts

Public ContactTakeshi Kaneko

Japan Clinical Trial Association N.A.

info@yakujihou.org0364574666

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026