Verification of changes in urinary vitamin D metabolites and beta-carotene due to vitamin D and beta-carotene supplementation in healthy subjects - Open-label study-

Verification of changes in urinary vitamin D metabolites and beta-carotene due to vitamin D and beta-carotene supplementation in healthy subjects - Open-label study- - Verification of changes in urinary vitamin D metabolites and beta-carotene due to vitamin D and beta-carotene supplementation in healthy subjects - Open-label study-

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000045653

Enrollment

Registered

2021-10-15

Start date

2021-10-19

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteer

Interventions

One tablet of each of the test foods (30.0 microgram of vitamin D and 1.9 mg of beta-carotene) will be taken once a day for 12 weeks.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Age: 20-64 2) BMI: 18.5 kg/m2-25.0 kg/m2 3) Subjects who giving informed consent

Exclusion criteria

Exclusion criteria: 1) Subjects who visit a hospital for treatment or take medicine for treatment. 2) Subjects who are under nutritional guidance or on a restricted diet. 3) Females who are pregnant, breast-feeding. 4) Subjects who with gelatin allergies. 5) Subjects who have taken vitamin D-containing or beta-carotene containing supplements at least 3 days per week for the past 3 months. 6) Subjects who have taken 3 or more servings of vegetable juice per week for the past 3 months. 7) Subjects who ate at least one piece of fish every day for the past 3 months. 8) Subjects who habitually engage in activities that involve tanning or sunbathing (leisure, commuting, etc.). 9) Females who are menstruating at the time of urine collection.

Design outcomes

Primary

Measure	Time frame
Concentrations of vitamin D metabolites in urine and beta-carotene in urine (0w,4w,8w,12w)	—

Secondary

Measure	Time frame
Vitamin D and beta-carotene sufficiency scores estimated from urinary markers(0w,4w,8w,12w)	—

Countries

Japan

Contacts

Public ContactAkiko Goto

Kenkoin Medical Corporation Foundation Kenkoin Clinic

akiko-goto@kenkoin.jp03-3573-1153

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026