Effects of Local Cryotherapy and the background factor of a patient on hypercytokinemia after orthognathic surgery.

Effects of Local Cryotherapy and the background factor of a patient on hypercytokinemia after orthognathic surgery. - Effects of Local Cryotherapy and the background factor of a patient on hypercytokinemia after orthognathic surgery.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000045635

Enrollment

Registered

2021-10-01

Start date

2010-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthognathic Surgery Cryotherapy Effect

Interventions

conventional compression with face mask. a water-circulating mask by Hilotherm.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: After bilateral sagittal split osteotomy (BSSO)

Exclusion criteria

Exclusion criteria: Patients found to have previously diagnosed with systematic inflammatory disease, to have used steroids or non-steroidal anti-inflammatory drugs (NSAIDs) preoperatively were excluded.

Design outcomes

Primary

Measure	Time frame
IL-6 protein level change postsurgical drainage fluid (before / after treatment)	—

Secondary

Measure	Time frame
pain Visual Analogic Scale change before / after treatment	—

Countries

Japan

Contacts

Public ContactKoichiro Sato

Tsurumi University School of Dental Medicine Department of Oral and Maxillofacial Surgery

sato-ki@tsurumi-u.ac.jp0455808332

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026