Usefulness of acetic acid NBI magnification endoscopy for colorectal tumors

A single-center prospective study to evaluate the diagnostic performance of NBI magnification under acetic acid spraying for colorectal tumors - A single-center prospective study to evaluate the diagnostic performance of NBI magnified endoscopy under acetic acid spraying for colorectal tumors(ANBI colon study)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000045621

Enrollment

300

Registered

2021-10-02

Start date

2021-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal tumor diagnosed as JNET classification 2B by NBI magnified endoscopic observation

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: a. Patients who are 18 years of age or older and who have received sufficient explanation and written consent for this study. b. Patients who have a colorectal tumor requiring treatment by colonoscopy and diagnosed as JNET 2B or 3 by NBI magnification. c. Patients who underwent NBI magnification under acetic acid spraying and crystal violet staining magnification of the region of interest, with the region diagnosed as JNET 2B or 3 as the region of interest, and both photographs were taken to show a well-focused pit pattern.

Exclusion criteria

Exclusion criteria: a. Recurrent lesions left over from endoscopic treatment b. Patients who have received systemic chemotherapy within 6 months prior to endoscopic examination. c. Patients with a history of radiation therapy to the abdominal pelvis. d. Patients with a history of ulcerative colitis. e. Patients who have been diagnosed with familial adenomatous polyposis. f. Those who are pregnant or may become pregnant. g. Those who are judged unsuitable by the doctor in charge.

Design outcomes

Primary

Measure	Time frame
Inter-methodological diagnostic agreement and inter-observer diagnostic agreement between NBI magnification endoscopic pit pattern diagnosis under acetic acid spraying and crystal violet stained magnification endoscopic pit pattern diagnosis of colorectal neoplasm	—

Secondary

Measure	Time frame
Results of pit pattern diagnosis by NBI under acetic acid spraying magnifying endoscopy and crystal violet-stained magnifying endoscopy , examination of findings specific to SM-d lesions as exploratory items, and adverse events.	—

Countries

Japan

Contacts

Public ContactTakeshi Shimizu

Sendai City Medical Center Sendai Open Hospital Gastroenterology

takeshi.shimizu@openhp.or.jp022-252-1111

Outcome results