None
Conditions
Interventions
Intake of powdered bifidobacteria for 12 weeks
Intake of powdered placebo for 12 weeks
Sponsors
Juntendo university graduate school of medicine Department of Microbiota Research
The Jikei University Kashiwa hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Adult female aged 30 years old or older
Exclusion criteria
Exclusion criteria: Individual who is applicable to any of the conditions below; 1. Taking regular aesthetic procedure or foods (except those who are able to continuously discontinue the act during the study). 2. Having skin problems, requiring medical care to their skin or taking treatment to diseases that could have an influence on their skin. 3. Having major allergic disease or being highly likely to develop those diseases 4. Being under sever diseases or having past history of those diseases. 5. Having medication allergy or severe food allergy. 6. Regularly taking foods, medication or supplement that would have an influence on gut microbiota (4 or more days a week of intake is regarded as regular use). 7. Heavy drinker 8. Smoking more than 20 cigarettes a day 9. Pregnant, willing to pregnant during the study period and continuous breast feeding 10. Currently participating to other clinical trial or past history within a month 11. Judged as not appropriate to this study by a responsible doctor or contributing doctors
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VISIA total score after oral intake of bifidobacteria | — |
Secondary
| Measure | Time frame |
|---|---|
| VISIA sub-scores, the balance of gut microbiota, the balance of skin microbiota, objective evaluation of skin condition, subjective evaluation of skin condition(VAS) after oral intake of bifidobacteria | — |
Countries
Japan
Contacts
Public ContactYuriko Nishikawa
Juntendo university graduate school of medicine Department of Microbiota Research
Outcome results
None listed