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The relationship between intervention in administration time of intraoperative analgesics and postoperative pain in wisdom teeth extraction under general anesthesia.

The effects of intervention in intraoperative pain management on postoperative pain relief in wisdom teeth extraction under general anesthesia. - The effects of intraoperative intervention on postoperative pain in minor surgery under general anesthesia.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000045554
Enrollment
40
Registered
2021-09-24
Start date
2021-05-21
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pericoronitis

Interventions

Group administered immediately before the end of surgery. Group administered 2 hours before the estimated end of the general anesthesia

Sponsors

Showa University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1)Patients with ASA PS1-2 who are scheduled to undergo bilateral mandibular tooth extraction under general anesthesia in Showa University Dental Hospital and will be hospitalized for three days. 2)Adult patients whose age at the time of consent is 20 to 60 years old. 3)Patients with mandibular impacted wisdom teeth mesial tilted who require bone removal and crown division during tooth extraction. 4)Patients who do not need bone removal for maxillary extraction when including maxillary wisdom teeth. 5)Patients who have given written consent to participate in this study.

Exclusion criteria

Exclusion criteria: 1)Patients with contraindications to acetaminophen Patients with aspirin asthma. Patients with severe liver disorder, renal disorder cardiac dysfunction, blood abnormality. Patients with peptic ulcer. Patients with a history of hypersensitivity to acetaminophen. 2)Patients using supplementary analgesics. 3)atients who are contraindicated for the administration of dental 2% lidocaine. Patients with hypertension, arteriosclerosis, heart failure, hyperthyroidism, diabetes mellitus and history of vascular spasm. 4)Patients with a history of hypersensitivity to general anesthetic. 5)Patients with painful oral complications that may affect the efficacy evaluation. 6)Patients scheduled for surgery other than tooth extraction. 7)Patients who cannot communicate and cannot express pain. Patients who have difficulty operating peripheral nerve stimulators. 8)Patients who had other wisdom teeth extracted before 45 days. 9)Patients who have used other non-steroidal anti-inflammatory drugs or antipyretic analgesics including topical drugs before 2 days. 10)Patients with BMI 30 or above. 11)Patients who are pregnant or breast-feeding.

Design outcomes

Primary

MeasureTime frame
Degree and presence of postoperative pain.

Secondary

MeasureTime frame
consciousness level, vital signs, adverse event

Countries

Japan

Contacts

Public ContactAkiko Nishimura

Showa university dental university Dental anesthesiology

nishim@dent.showa-u.ac.jp0337871151

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026