Type 2 diabetes mellitus
Conditions
Interventions
10mg elobixibat treatment for 12 weeks
Sponsors
Kurume University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Diagnosis of chronic constipation as defined by Rome IV criteria. Type 2 diabetes with HbA1c less than 10%. 20 years of age or older. Patient who can provide written informed consent before enrollment. Patient who had received a stable antidiabetic regimen for at least 3 months prior to study entry. Patient who can obtain blood and urine samples for follow-up before and after the eloboxibat treatment.
Exclusion criteria
Exclusion criteria: Pregnant or lactating women Patient with intestinal obstruction due to tumor or hernia etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bowel movements (frequency of bowel movements, Bristol Scale) | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood glucose,HbA1c,LDL,HDL,triglyceride,fatty acid fraction,AST,ALT,gammaGTP,Total bile acid,TSH,FT3,FT4,CRP,UA, Ferritin,body weight | — |
Countries
Japan
Contacts
Public ContactSatoko Yoshinobu
Kurume University School of Medicine Department of Internal Medicine, Division of Endocrinology and Metabolism
Outcome results
None listed