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Early Chronic Pancreatitis Findings on EUS are Associated with Pancreatic Fibrosis, Chronic Inflammation, and Atrophy

Early Chronic Pancreatitis Findings on EUS are Associated with Pancreatic Fibrosis, Chronic Inflammation, and Atrophy - EUS findings of Early CP and Histology

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000045497
Enrollment
221
Registered
2021-09-16
Start date
2021-10-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intraductal papillary mucinous neoplasm, pancreatic neuroendocrine neoplasm, pancreatic ductal carcinoma in body/tail of the pancreas, and distal cholangiocarcinoma

Interventions

None listed

Sponsors

Division of Gastroenterology, Department of Internal Medicine Kobe University Graduate School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Patients aged over 20 years 2)The clinical data of 221 patients with pancreatic tumor or distal cholangiocarcinoma who underwent preoperative EUS and pancreatic surgery from January 2010 to November 2020 were collected.

Exclusion criteria

Exclusion criteria: 1)Patients who have requested not to participate in this study based on public information. 2) Patients whose pathology specimens do not contain evaluable pancreatic tissue. 3) Patients deemed inappropriate by the principal investigator.

Design outcomes

Primary

MeasureTime frame
Our primary hypothesis testing evaluated the statistical association between EUS findings (hyperechoic foci/stranding or lobularity) and histology (pancreatic fibrosis, inflammation, or atrophy).

Countries

Japan

Contacts

Public ContactNoriko Inomata

Kobe University Graduate School of Medicine Gastroenterology

inomat@med.kobe-u.ac.jp0783826305

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026