Malignant pleural mesothelioma
Conditions
Interventions
Intensity-modulated radiotherapy
Sponsors
Kyoto University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: - Malignant pleural mesothelioma which is macroscopic-completely resected with pleurectomy/decortication - Epithelioid or biphasic histology - Pathological stage of IA to IIIA (= T1-3N0-1M0) - No evidence of distant metastasis - Performance status of 0-1 - Neo-adjuvant or adjuvant chemotherapy is completed
Exclusion criteria
Exclusion criteria: - Synchronous cancer or metachronous cancer with disease-free interval less than 5 years - A history of thoracic radiotherapy - Obvious pulmonary fibrosis and interstitial pneumonia - Serious cardiac disease, serious arrhythmia, serious infectious disease, neuropsychiatric disease - Diabetes mellitus difficult to control, or diseases requiring steroids - Patients who have difficulty in understanding the consent document or in expressing their intention to receive treatment - Other cases deemed inappropriate by the principal investigator/investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Completion rate of the treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| Acute toxicities, late toxicities, overall survival, local control, progression-free survival, and dose-volumetric factors | — |
Countries
Japan
Contacts
Public ContactNoriko Kishi
Kyoto University Graduate School of Medicine Radiation Oncology and Image-applied Therapy
Outcome results
None listed