Examination of changes in nutritional status and body composition after SGLT2 inhibitor administration for patients with liver cirrhosis and with diabetes

Examination of changes in nutritional status and body composition after SGLT2 inhibitor administration for patients with liver cirrhosis and with diabetes - Changes in nutritional status and body composition after SGLT2 inhibitor administration

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000045412

Enrollment

Registered

2021-09-20

Start date

2020-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non alcoholic fatty liver disease diabetes mellites

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) 20 years old and over (2) Compensatory cirrhosis with diabetes (Child-Pugh classification A or B, regardless of the cause of cirrhosis) (3) Those who are newly started to administer SGLT2 inhibitors

Exclusion criteria

Exclusion criteria: (1) Under 20 years old (2) Decompensated cirrhosis (Child-Pugh classification C) (3) Patients who are already taking SGLT2 inhibitors or who have been found to be allergic to SGLT2 inhibitors in the past (4) Patients using insulin preparations for diabetes treatment (5) Patients who are pregnant or may become pregnant (6) Other patients who the attending physician has determined to be unable to participate in the study

Design outcomes

Primary

Measure	Time frame
Changes in nutritional status due to SGLT2 inhibitor treatment in patients with liver cirrhosis	—

Secondary

Measure	Time frame
Changes in body composition (water, fat mass, muscle mass) after 6 months Changes in liver hardness and liver reserve after 6 months	—

Countries

Japan

Contacts

Public ContactTakuya Kuwashiro

Saga Medical School Hepatology, Diabetes and Endocrinology

f8451@cc.saga-u.ac.jp0952342362

Outcome results