Evaluation of the chronological changes of plasma levobupivacaine concentration after performing M-TAPA.

Evaluation of the chronological changes of plasma levobupivacaine concentration after performing M-TAPA. - Evaluation of the chronological changes of plasma levobupivacaine concentration after performing M-TAPA.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000045406

Enrollment

Registered

2021-09-13

Start date

2021-09-13

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The patients undergoing abdominal surgery longer than 2 hours under general anesthesia in conjunction with M-TAPA.

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients undergoing abdominal surgery under generalanesthesia in conjunction with bilateral M-TAPA using 25ml 0.25% levobupivacaine mixed with 5ug/ml epinephrine.

Exclusion criteria

Exclusion criteria: 1. ASA-PS >=3 2. Allergy to local anesthetics or epinephrine 3. Body weight <=50 kg 4. Existing hepatopathy or neuropathy 5. Pregnancy 6. Albumine <=3 g/dL 7. Other patients who are judged inappropriate by the investigator

Design outcomes

Primary

Measure	Time frame
The plasma levobupivacaine concentration at 10, 20, 30, 45, 60, 120 minutes after performing M-TAPA.	—

Secondary

Measure	Time frame
1. Correlation with plasma local anesthetic concentration and patient's characteristics. 2. Adverse events occurring within 12 hours after M-TAPA performance.	—

Countries

Japan

Contacts

Public ContactKatsuhiro Aikawa

Hokkaido university hospital Anesthesiology

katsuhiro.aikawa@med.hokudai.ac.jp+81-11-706-7861

Outcome results