Investigate the relationship between the individual differences in the effects of continuous ubiquinol (reduced CoQ10) supplementation on improving QOL and cognitive function and the single nucleotide polymorphisms in CoQ10 metabolism-related genes.

Investigate the relationship between the individual differences in the effects of continuous ubiquinol (reduced CoQ10) supplementation on improving QOL and cognitive function and the single nucleotide polymorphisms in CoQ10 metabolism-related genes. - Investigation of the relationship between the individual differences in the effects of continuous ubiquinol supplementation on improving QOL and cognitive function and the single nucleotide polymorphisms.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000045397

Enrollment

170

Registered

2021-09-07

Start date

2021-09-07

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nothing

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: One hundred seventy people participated in the "Relationship between the absorption of ubiquinol supplement and the genetic diversity for participants in the Ubiquinol Health Examination (SNP Study)" (2016) and in the Ubiquinol Health Examination (from 2013 to 2018). The SNP Study was approved by the Wayo Women's University Human Research Ethics Committee (No. 1614).

Exclusion criteria

Exclusion criteria: Those who were assessed to have a low intake rate of ubiquinol supplement based on serum CoQ10 levels in this study

Design outcomes

Primary

Measure	Time frame
Relationship between SNPs and SF-36 by the continuous ubiquinol supplementation	—

Secondary

Measure	Time frame
Relationship between SNPs and Digit Symbol Substitution Test by the continuous ubiquinol supplementation	—

Countries

Japan

Contacts

Public ContactToshikazu Suzuki

Wayo Women's University Department of Health and Nutrition

t-suzuki@wayo.ac.jp043-371-1547

Outcome results