Relationship between hemodynamic instability and glycocalyx in patients requiring continuous renal replacement therapy: a single-center prospective observational study

Relationship between hemodynamic instability and glycocalyx in patients requiring continuous renal replacement therapy: a single-center prospective observational study - Relationship between hemodynamic instability and glycocalyx in patients requiring continuous renal replacement therapy: a single-center prospective observational study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000045386

Enrollment

Registered

2021-09-27

Start date

2021-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients requiring continuous renal replacement therapy

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients requiring continuous renal replacement therapy at Department of Emergency and Critical Care Medicine,Tohoku University Hospital

Exclusion criteria

Exclusion criteria: 1) Patients with malignant tumors 2) Patients without invasive arterial pressure monitoring 3) Patients being judged to be inappropriate for participation by attending physicians. 4) patients who used percutaneous cardiopulmonary support

Design outcomes

Primary

Measure	Time frame
Changes of the blood concentration of syndecan-1, which is a component of glycocalyx, between those before the introduction or circuit changes and thereafter.	—

Countries

Japan

Contacts

Public ContactRyota Ogasawara

Tohoku University Graduate School of Medicine Emergency and Critical Care Medicine

ryota.ogasawara.e1@tohoku.ac.jp+81-22-717-7688

Outcome results