Comparison of Nasal pillow noninvasive positive pressure ventilation and high flow nasal therapy for the treatment and prevention of post extubation failure in intensive care patients

Comparison of Nasal pillow noninvasive positive pressure ventilation and high flow nasal therapy for the treatment and prevention of post extubation failure in intensive care patients - Comparison of Nasal pillow noninvasive positive pressure ventilation and high flow nasal therapy for the treatment and prevention of post extubation failure in intensive care patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000045352

Enrollment

100

Registered

2021-09-02

Start date

2019-09-13

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ICU patients

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who underwent NP-NPPV or HFNT after extubation to prevent post-extubation failure after more than 24 hours of ventilatory management after surgery

Exclusion criteria

Exclusion criteria: Non-operative patients, patients who did not require ventilatory management for more than 24 hours postoperatively, patients younger than 18 years, patients who used both NP-NPPV and HFNT, tracheostomy, head and neck surgery, significant neurological disorders, patients who used NPPV or HFNT preoperatively

Design outcomes

Primary

Measure	Time frame
The primary outcomes were respiratory parameters (PO2/FIO2 ratio, PCO2, respiratory rate) and tolerability of each interface immediately after extubation and 24 hours later.	—

Secondary

Measure	Time frame
The secondary outcomes were the duration of device use, the rate of device withdrawal after 24 hours, and the incidence of skin injury associated with the interface.	—

Countries

Japan

Contacts

Public ContactYoshifumi Ohchi

Oita University Department of Anesthesiology and Intensive Care, Faculty of Medicine

ohchi-yo@oita-u.ac.jp0975865943

Outcome results