Esophageal cancer Esophagogastric junction cancer
Conditions
Interventions
Patients are randomized into two groups. One of the groups receives two-lung ventilation during the thoracic part of minimally invasive esophagectomy.
The other group receives one-lung ventilation.
Sponsors
Juntendo University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Participants should consent to receive the combination of epidural and general anesthesia. 2) Participants should give written informed consent after receiving enough information on the study. 3) Close member of the family may give consent in case participants have trouble understanding the information on the study.
Exclusion criteria
Exclusion criteria: 1) Morbidly obese 2) Severe chronic obstructive lung disease 3) Interstitial pneumonia 4) Giant lung cyst 5) Those who have tracheostomy 6) Those in whom hypercapnia cannot be accepted (e.g., pulmonary hypertension, intracranial hypertension) 7) Those whom researchers consider as not appropriate for participants
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum interleukin-6 concentration at the end of thoracic part of minimally invasive esophagectomy | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcomes include postoperative pulmonary complication, reintubation, days in the intensive care unit, and days under mechanical ventilation. | — |
Countries
Japan
Contacts
Public ContactSeiji Ishikawa
Juntendo University, School of Medicine Department of Anesthesiology and Pain Clinic
Outcome results
None listed