The clinical study of alveolar bone tissue engineering for severely atrophic alveolar bone using autologous bone marrow stromal cells

The clinical study of alveolar bone tissue engineering for severely atrophic alveolar bone using autologous bone marrow stromal cells - Alveolar bone regeneration using bone marrow stromal cells

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000045309

Enrollment

Registered

2021-08-31

Start date

2013-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

severely atrophic alveolar bone

Interventions

bone marrow cell harvest - cell cultured bone transplantation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Subjects showed severely atrophic maxilla or mandible, which require bone transplantation for dental implant insertion. The width of alveolar bone at the installation sites was less than 5 mm. In the maxilla, the distance between the alveolar ridge and the sinus floors was less than 5 mm. Similarly, in the mandible, the distance between the ridge and mandibular canal was less than 5 mm.

Exclusion criteria

Exclusion criteria: Patients with diabetes and/or autoimmune diseases,

Design outcomes

Primary

Measure	Time frame
Amount of alveolar bone regeneration assessing by CT images 6 months and over 5 years after the transplantation.	—

Countries

Japan

Contacts

Public ContactIzumi Asahina

Nagasaki University Graduate School of Biomedical Sciences Department of Regenerative Oral Surgery

asahina@nagasaki-u.ac.jp095-819-7701

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026