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Epidemiological Study for Cases with Irreversible Hypoxic Encephalopathy and Brain Death in Japanese Metropolitan Tertiary EDs

Epidemiological Study for Cases with Irreversible Hypoxic Encephalopathy and Brain Death in Japanese Metropolitan Tertiary EDs - Epidemiological Study for Cases with Irreversible Hypoxic Encephalopathy and Brain Death in Japanese Metropolitan Tertiary EDs

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000045286
Enrollment
500
Registered
2021-08-27
Start date
2009-10-02
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

severe brain damage, poor neurological prognosis After Cardiopulmonary Arrest

Interventions

None listed

Sponsors

St. Marianna University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) The patients with BSR[-] who suffered brain hemorrhage/infarction 2) severe neurological prognosis or the OHCA patients who survived for more than 72 hours but with poor neurologic outcomes

Exclusion criteria

Exclusion criteria: 1) The patients who experienced CPA in our hospitals (i.e., in-hospital CPA) or who had suffered CPA in other hospitals and then transferred to our facilities 2) The cases in a potentially reversible coma (e.g., acute alcohol/drug addiction, hypothermia, sepsis, uremia, encephalopathy due to metabolic and endocrine diseases, use of neuromuscular blocking or high-dose sedative agents) 3) Children under the age of 16 4) CPA patients with a history of medical errors or social problems

Design outcomes

Primary

MeasureTime frame
Evaluation of the relationship between the presence or absence of residual brainstem reflex and prognosis

Secondary

MeasureTime frame
Evaluation of changes in medical staff / patients in the end-of-life treatment policy

Countries

Japan

Contacts

Public ContactHaruaki Wakatake

St. Marianna University Yokohama Seibu Hospital Department of Emergency and Critical Care Medicine

haruwakatake@gmail.com045-366-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026