Comparative test on the preventive effect of chlorine dioxide gas on infections such as influenza

Randomized placebo-controlled crossover controlled trials for prevention of influenza and other infections with chlorine dioxide gas generating product - Influenza prevention effect test

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000045276

Enrollment

324

Registered

2021-08-26

Start date

2020-10-13

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Influenza

Interventions

Installation of chlorine dioxide gas generating product for 2 months =&gt

(Washout period for 2 weeks) =&gt

Placebo installation for 2 months Placebo installation for 2 months =&gt

Installation of chlorine dioxide gas generating product for 2 months

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Students who have received sufficient explanation about this study, fully understood it, and obtained written consent by the parent's free will.

Exclusion criteria

Exclusion criteria: Students with chemical sensitivity to chlorine bleach and chlorination of pools. In addition, students who are judged by the principal investigator to be inappropriate as research subjects.

Design outcomes

Primary

Measure	Time frame
Cumulative incidence rate of influenza	—

Secondary

Measure	Time frame
Absence days, Non-influenza respiratory infections: Incidence rate of each respiratory symptom (fever, headache, cough / nasal juice), Infectious gastroenteritis: Rate of infectious gastroenteritis, and gastroenteritis incidence (diarrhea, abdominal pain, vomiting / nausea)	—

Countries

Japan

Contacts

Public ContactTakanori Miura

Juntendo University Hospital Pediatrics

t.miura.hg@juntendo.ac.jp03-3813-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026