Cerebral aneurysms, cerebral arteriovenous malformations, epilepsy
Conditions
Interventions
None listed
Sponsors
RIKEN Center for Brain Science
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients with established diagnosis of cerebrovascular disease and epilepsy and a control group (patients who were treated for conditions other than the target diseases) will be included in the analysis. If intrafamilial clustering or inherited disease is strongly suspected, and the importance and validity of linkage analysis are considered to be very high, family members (siblings, parents, children, other relatives etc.) will be included in the analysis of this study. 2) Patients who have visited an affiliated to the study hospital that was approved by the Ethics Committee to conduct the study. 3) Regardless of age or gender. 4) Adults who have given their written consent. Minors under 20 years of age or patients with cerebrovascular diseases and epilepsy who cannot be held legally responsible will require a consent of their parents or guardians.
Exclusion criteria
Exclusion criteria: Exclude cases where the above eligibility criteria are not met.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Elucidate disease pathogenesis by identifying disease-causing, disease-susceptibility, and modifying genetic mutations. | — |
Secondary
| Measure | Time frame |
|---|---|
| Paired tissue and blood analysis can reveal the presence of somatic mutations that are important for pathogenesis. | — |
Countries
Japan
Contacts
Public ContactHirofumi Nakatomi
RIKEN Center for Brain Science, Biomedical neural dynamics collaboration laboratory
Outcome results
None listed