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Monitoring of TCR clonotype and diversity of CD8+PD-1+ T-cells in locally-advanced non-small cell lung cancer: A Biomarker Study.

Monitoring of TCR clonotype and diversity of CD8+PD-1+ T-cells in locally-advanced non-small cell lung cancer: A Biomarker Study. - TCR clonotype and diversity of CD8+PD-1+ T-cells in locally-advanced non-small cell lung cancer

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000045171
Enrollment
100
Registered
2021-08-18
Start date
2020-03-16
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

locally-advanced non-small cell lung cancer patients

Interventions

None listed

Sponsors

National Cancer Center Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Locally adnced NSCLC patiens. 2) Treatment with CRT. 3) Written Informed consent

Exclusion criteria

Exclusion criteria: 1) Patients judged as inappropriate for the study by the investigator

Design outcomes

Primary

MeasureTime frame
To evaluate the TCR clonotype on CD8+PD-1+ T-cells during CRT

Countries

Japan

Contacts

Public ContactTatsuya Yoshida

National Cancer Center Hospital Department of thoracic oncology

tatyoshi@ncc.go.jp03-3542-2511

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026