New controlled ovarian stimulation (COS) method for polycystic ovary syndrome (PCOS) avoids ovarian hyperstimulation syndrome (OHSS) and produces higher oocyte quality resulting in highest cumulative pregnancy at one cycle.

New controlled ovarian stimulation (COS) method for polycystic ovary syndrome (PCOS) avoids ovarian hyperstimulation syndrome (OHSS) and produces higher oocyte quality resulting in highest cumulative pregnancy at one cycle. - New controlled ovarian stimulation (COS) method for polycystic ovary syndrome (PCOS) avoids ovarian hyperstimulation syndrome (OHSS) and produces higher oocyte quality resulting in highest cumulative pregnancy at one cycle.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000045145

Enrollment

Registered

2021-08-12

Start date

2017-12-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovary syndrome(PCOS)

Interventions

In the new COS protocol, we started with FSH injections (150IU/ml) and then continued with HMG (150IU/ml) until the injection of the trigger. GnRH antagonist shots were started when the leading follic

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1)Patient of Polycystic ovary syndrome(PCOS) 2)Married women

Exclusion criteria

Exclusion criteria: 1)Patients with Severe Type2 diabetes. 2)Patients and Husband who can not obtain written informed consent. 3)Patients judged to be inappropriate for the study by the physicians.

Design outcomes

Primary

Measure	Time frame
To establish a new controlled ovarian stimulation (COS) protocol for polycystic ovary syndrome (PCOS) that does not cause ovarian hyper stimulation syndrome (OHSS) while maintaining egg quality.	—

Secondary

Measure	Time frame
1)No adverse and after effect for ovarian function following using this COS 2)Comparison of proportions of fertilization, pregnancy and abortion with those of base line levels.	—

Countries

Japan

Contacts

Public ContactAtsushi Tanaka

Saint Mother Clinic Medical office

incho@stmother.com093-601-2000

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026