Skip to content

Pathological analysis of ECRS by RNA-seq

Pathological analysis of ECRS by RNA-seq - R-ECRS

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000045139
Enrollment
10
Registered
2021-10-01
Start date
2021-10-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

eosinophilic chronic rhino sinusitis

Interventions

mepolizumab 100mg/4 weeks for 4 months

Sponsors

International University of Welfare and Health, Narita hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. patients who are diagnosed as ECRS 2. patients who agree to be included in this trial by a document 3. patients who are older than 20 years old 4. patients who need surgery for his or her ECRS

Exclusion criteria

Exclusion criteria: 1. patients who do not agree to be included in this trial 2. patients who have had mepolizumab therapy for his or her ECRS 3. patients who are not able to obtain his or her blood or surgical samples

Design outcomes

Primary

MeasureTime frame
identification of genes which are highly expressed in ECRS

Secondary

MeasureTime frame
identification of molecular pathways which are involved in the mechanisms of ECRS

Countries

Japan

Contacts

Public ContactKoichi Hirose

International University of Welfare and Health, Narita hospital Department of Allergy and Rheumatology

hirose-kh@iuhw.ac.jp0476-35-5600

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026