Improvements on glycation by thermal effects of balneotherapy

Improvements on glycation by thermal effects of balneotherapy - Improvements on glycation by thermal effects of balneotherapy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000045115

Enrollment

Registered

2021-08-10

Start date

2019-10-12

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with impaired glucose tolerance Healthy subjects Patients with chronic pain

Interventions

The subjects stayed at the hotel with hot springs for one-week and took hot spring baths twice a day for 20 min (balneotherapy).

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Age: 20-75 years 2)Male or Female 3)Provided written consent to participate in this study

Exclusion criteria

Exclusion criteria: 1) Current smoker 2) Alcohol intake

Design outcomes

Primary

Measure	Time frame
Changes in the state of red blood cell deformation by dark field microscopy	—

Secondary

Measure	Time frame
Changes in AGEs levels Changes in the oxidative stress (reactive oxygen metabolites, d-ROM), antioxidant power (biological antioxidant potential, BAP), and potential antioxidant capacity (BAP/d-ROM ratio)	—

Countries

Japan

Contacts

Public ContactSatoko Shiwa

International Foundation of Comprehensive Medicine Chiyoda International Clinic

shiwa-ifcm@nifty.com03-5577-6841

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026