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Effect of adjuvant chemotherapy on localized malignant giant cell tumor of bone: a systematic review

Effect of adjuvant chemotherapy on localized malignant giant cell tumor of bone: a systematic review - Effect of adjuvant chemotherapy on localized malignant giant cell tumor of bone: a systematic review

Status
Active, not recruiting
Phases
Unknown
Study type
Unknown
Source
JPRN
Registry ID
JPRN-UMIN000045042
Enrollment
Unknown
Registered
2021-08-02
Start date
2021-08-02
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

malignant giant cell tumor of bone

Interventions

None listed

Sponsors

Nara Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who underwent surgery alone for the primary tumor of malignant GCTB and chemotherapy for distant metastases that occurred during the course of the disease were classified as the surgery alone group. Regarding the number of deaths, only deaths due to tumor were counted. Only literatures written in English and Japanese were included, and no restrictions were placed on the year of publication.

Exclusion criteria

Exclusion criteria: Patients with distant metastasis at the time of diagnosis of malignant GCTB were excluded. Patients with an unclear prognosis were also excluded.

Design outcomes

Primary

MeasureTime frame
Number of patients treated with surgery and adjuvant chemotherapy for primary malignant GCTB and number of tumor-related deaths, number of patients who underwent surgery alone for primary malignant GCTB and number of tumor-related deaths; number of patients treated with surgery and adjuvant chemotherapy for secondary malignant GCTB and number of tumor-related deaths, number of patients who underwent surgery alone for secondary malignant GCTB and number of tumor-related deaths;

Countries

Japan,Europe

Contacts

Public ContactShinji Tsukamoto

Nara Medical University Department of Orthopaedic Surgery

sh104@naramed-u.ac.jp+81-744-22-3051

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026