Healthy adults
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Healthy males and females
Exclusion criteria
Exclusion criteria: -Pregnancies -Diseases with abnormal blood vessels -Severe coldness -Subjects who are participating in a study with physical load that affects the measurement results of this study -Subjects who use sleeping pills, antiallergic drugs, analgesics, hormones, gastric acid secretion inhibitors, and other drugs for diseases -Implants and dentures in the upper front gingiva -Total dentures -Subjects with wound in the measurement site of the skin -Subjects with allergy symptoms such as hay fever, rhinitis, atopic dermatitis -Subjects deemed inappropriate to participate in this study by the principle investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin and gingival blood flow | — |
Secondary
| Measure | Time frame |
|---|---|
| Vascular function, blood pressure, electrocardiogram, pulse waves, heart sounds, cardiac output, stratum corneum water content, skin viscoelasticity, skin color, PMA Index, color of gingiva probing pocket depth (PPD), gingival index (GI), bleeding on probing (BOP), dental plaque, height, weight, abdominal circumference, number of red blood cells, blood pigment content, hematocrit, blood lipids, liver function, fasting blood sugar, HbA1C, urine sugar, urine protein | — |
Countries
Japan
Contacts
Kao Corporation Personal Healthcare Products Research