Healthy adults
Conditions
Interventions
Ingredient A-containing food (12 weeks)
Ingredient B-containing food (12 weeks)
Ingredient-free food (12 weeks)
Sponsors
Hokkaido Information University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Subjects who can make self-judgment and are voluntarily giving written informed consent. (2) From 50 to 65 years healthy men and women.
Exclusion criteria
Exclusion criteria: (1) Subjects who are under medication for dementia, Alzheimer's disease, psychiatric disorder and cerebrovascular disease. (2) Subjects who have a history or are suspected patient of cranial nerve disease and psychiatric disorders. (3) Subjects who have serious cerebrovascular, cardiac, hepatic, renal, gastrointestinal diseases, and/or affected with infectious diseases requiring reports to the authorities. (4) Subjects who are with diabetes mellitus. (5) Subjects who have major surgical history relevant to the digestive system such as gastrectomy, gastrointestinal suture, or intestinal resection. (6) Subjects who are with systolic blood pressure of less than 90 mmHg. (7) Subjects who have unusually high and/or low blood pressure and/or abnormal hematological data. (8) Pre- or post-menopausal women complaining of obvious physical changes. (9) Subjects who experienced unpleasant feeling during drawing blood. (10) Subjects who have difficulty in blood collection from peripheral veins. (11) Subjects whose blood hemoglobin level is less than 13 g/dL for males and less than 12 g/dL for female. (12) Subjects who have metal such as aneurysm clips, bone fixation plates in the head.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cerebral blood flow | — |
Countries
Japan
Contacts
Public ContactYumi Nakamura
Suntory global innovation center limited. Research Institute
Outcome results
None listed