A single-center prospective study on the safety of endobiliary radiofrequency ablation of hilar malignant biliary stenosis

A single-center prospective study on the safety of endobiliary radiofrequency ablation of hilar malignant biliary stenosis - Safety of endobiliary RFA for hilar malignant biliary stenosis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000044973

Enrollment

Registered

2021-07-27

Start date

2021-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hilar malignant biliary stenosis

Interventions

endobiliary radiofrequency ablation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Unresectable malignant hilar biliary obstruction with pathological proof 2.Bismuth classification 2,3,4 3.ECOG performance status 0-3 4.Given written informed consent

Exclusion criteria

Exclusion criteria: 1.Patients in whom the endoscope cannot reach the duodenal papilla 2.Patients with jaundice or cholangitis that cannot be controlled by biliary drainage 3.Patients with serious complications in other organs: ASA classification of 3 or higher 4.Patients with a life expectancy of less than 3 months 5.Patients with a history of surgical gastrointestinal reconstruction 6.Patients with significant invasion of the hepatic artery by the tumor 7.Patients who are deemed inappropriate by the researcher

Design outcomes

Primary

Measure	Time frame
Adverse events	—

Countries

Japan

Contacts

Public ContactArata Sakai

Kobe University Hospital Division of gastroenterology, Department of Internal medicine

asakai@med.kobe-u.ac.jp+81-78-382-5774

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026