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Effects of two months of lactotripeptide (LTP) intake and aerobic exercise intervention on fatigue, vascular function and exercise capacity: A randomized controlled trial

Effects of two months of lactotripeptide (LTP) intake and aerobic exercise intervention on fatigue, vascular function and exercise capacity: A randomized controlled trial - The effect of exercise training and lactotripeptides

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000044896
Enrollment
80
Registered
2021-08-15
Start date
2021-08-02
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Middle-aged and older adults

Interventions

Placebo (casein) ingestion, 2 months Lactotripeptides ingestion, 2 months Placebo (casein) ingestion, 2 months Aerobic exercise (moderate intensity, 30-50 min, 3-6 d/w), 2 months Lactotripeptides ing

Sponsors

Factory of Health and Sports Science, University of Tsukuba
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Not restricted by a doctor from exercising 2. Not doing moderate- to vigorous-intensity aerobic training 3. Not participate in another clinical trial in one year 4. Not have lactose intolerance 5. Can agree with contents of study 6. Not take angiotensin-converting enzyme inhibitor and angiotensin II receptor blocker

Exclusion criteria

Exclusion criteria: 1. Care-dependent or support-dependent on a Japanese long-term care insurance system 2. Have severe heart disease, cerebrovascular disease, and renal dysfunction 3. Medical doctors can not agree with participation in the study 4. Limited mobility

Design outcomes

Primary

MeasureTime frame
Fatigue (2 months after intervention)

Secondary

MeasureTime frame
Vascular function (2 months after intervention) Aerobic capacity (2 months after intervention) Physical performance (2 months after intervention) Biochemical blood test (2 months after intervention)

Countries

Japan

Contacts

Public ContactMasaki Yoshioka

University of Tsukuba Factory of Health and Sports Science

masakiyoshioka1129@gmail.com+81-29-853-5990

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026