Effects of Kampo medicine Hochuekkito on fatigue and health-related quality of life in hemodialysis patients with chronic kidney disease: a pilot study

Effects of Kampo medicine Hochuekkito on fatigue and health-related quality of life in hemodialysis patients with chronic kidney disease: a pilot study - Effects of Kampo medicine Hochuekkito on fatigue and health-related quality of life in hemodialysis patients with chronic kidney disease: a pilot study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000044853

Enrollment

Registered

2021-07-13

Start date

2021-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney disease stage G5D

Interventions

Hochuekkito extract granules 7.5g/day for 2 months

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients who have obtained their consent 2. Age >= 20 y.o. 3. Chronic kidney disease patients with hemodialysis for more than 3 months 4. Chalder Fatigue Scale (CFS) >= 19 5. Patients who can answer the questionnaire

Exclusion criteria

Exclusion criteria: 1. Pregnant or possibly pregnant 2. A history of allergies to hochuekkito 3. Severe hypertension (>= 180/110 mmHg) 4. Onset of cardiovascular disease within 1 month 5. Severe complications including blood disorders, active malignancies, infectious diseases, thyroid disorders, and depression 6. Using steroids, immunosuppressants (e.g. cyclosporine), and glycyrrhizin 7. Using other Kampo medicines 8. Participating in another clinical trial 9. Participants who are judged to be inappropriate

Design outcomes

Primary

Measure	Time frame
Chalder fatigue scale	—

Countries

Japan

Contacts

Public ContactKazushi Uneda

Aizu Medical Center, Fukushima Medical University School of Medicine Department of Kampo Medicine

uneda@fmu.ac.jp0242-75-2100

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026