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Detection of novel biomarkers in patients with interstitial pneumonia or acute exacerbation of interstitial pneumonia.

Detection of novel biomarkers in patients with interstitial pneumonia or acute exacerbation of interstitial pneumonia. - Detection of novel biomarkers in patients with interstitial pneumonia or acute exacerbation of interstitial pneumonia.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000044825
Enrollment
300
Registered
2021-09-08
Start date
2021-09-08
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with interstitial pneumonias or acute exacerbation of interstitial pneumonias

Interventions

None listed

Sponsors

Hamamatsu University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients, who were diagnosed as interstitial pneumonias (IPs) or acute exacerbation of interstitial pneumonias from 1980, and whose serum were available, were included. IPs were diagnosed based on the presence of chest fine crackles, high-resolution computed tomography findings, and preexisting biomarkers. The diagnosis of acute exacerbation of IPs were based on diagnostic criteria for acute exacerbation of idiopathic pulmonary fibrosis (Collard H et al. AJRCCM 2016).

Exclusion criteria

Exclusion criteria: Patients with severe heart failure or excessive fluid overload were excluded.

Design outcomes

Primary

MeasureTime frame
Overall survival

Secondary

MeasureTime frame
Diagnostic capacity, percent predicted forced vital capacity (%FVC) and diffusion lung capacity for carbon monoxide (%DLCO), the partial pressure of arterial oxygen (PaO2) at rest and minimum partial oxygen saturation during the 6-min walk test (6MWT), serum KL-6/SP-D, HRCT findings, findings on lung specimens, response to treatments

Countries

Japan

Contacts

Public ContactNoriyuki Enomoto

Hamamatsu University School of Medicine Health administration center

norieno@hama-med.ac.p+81-53-435-2263

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026