Primary Lateral Sclerosis
Conditions
Interventions
None listed
Sponsors
Toho University Omori Medical Center
Department of Neurology, Fukushima Medical University School of Medicine, Fukushima, Japan. Rehabilitation Center, Jichi Medical University Hospital, Shimotsuke, Japan. Department of Neurology, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan. Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan. Department of Neurology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Upper motor neuron dysfunction of unknown cause are observed in at least two of the three regions of cranial nerves, upper limbs, and lower limbs regardless of the duration of illness, and needle electromyography shows normal or active lower motor neuron lesions. Patients meet all of the following. 1) Japanese is the first language. 2) You can sign the consent form. If you cannot sign due to weakness of the upper limbs, or if you cannot answer due to dysarthria, the signature of their substitute is acceptable. 3) Age at diagnosis is 20 years or older 4) No family history or consanguineous marriage.
Exclusion criteria
Exclusion criteria: 1) If you have cognitive decline or deafness including their substitute. 2) When the researchers decide that he/she cannot express his/her intention accurately. 3) If you do not agree to this study. 4) In cases of death during the course 5) When the researchers judge inappropriate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We evaluate consistency of scores between evaluators, intra-rater reliability, face-to-face consultation, and telephone listening for all 12 items of PLSFRS and their total scores. | — |
Countries
Japan
Contacts
Public ContactMasaru Yanagihashi
Toho University Faculty of Medicine Department of Neurology
Outcome results
None listed