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Modulation of Interhemispheric Interaction by I-wave Periodicity Repetitive TMS

Distinct Neural Pathways of I-wave Facilitation Induced by TMS: Perspectives from Interhemispheric Interaction - I-wave-IHF Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000044802
Enrollment
15
Registered
2021-07-09
Start date
2021-12-15
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adult

Interventions

I-wave Periodicity Repetitive Transcranial Magnetic Stimulation

Sponsors

TOHOKU University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Healthy right-handed adults (aged between 20-65 years old) with no history or current signs of neurological or musculoskeletal impairment, with no risk or contraindications regarding to the rTMS Screening Questionnaire.

Exclusion criteria

Exclusion criteria: Those who use medical electrical equipment (biological implantable medical electrical equipment such as pacemakers, life-supporting medical electrical equipment such as artificial heart-lung machine, wearable medical electrical equipment such as electrocardiograms); Those who are pregnant or immediately after childbirth; Those with infectious diseases; Those with acute (painful) illness; Those with hypothermia; Those with blood circulation disorders; Those with orthopedic disorders in the upper limbs; Those who have had surgery on the upper limbs in the past; Those with visual impairment including difficult-to-correct vision loss, narrowing of the visual field, and color vision deficiency; Those with a history of central neurological or psychiatric disorders such as stroke, head injury, dementia, motor developmental retardation, and schizophrenia; Those with motor and sensory disorders of the upper limbs; Those who have subjective symptoms such as extreme optical illusion and decreased visual acuity due to eye strain.

Design outcomes

Primary

MeasureTime frame
The amplitude of MEP evoked by single-pulse and paired-pulse TMS at 4 timepoints of the experiment: Pre-iTMS, Half-iTMS, Post-iTMS and 10min-Later-iTMS.

Countries

Japan

Contacts

Public ContactDongting Tian

Tohoku University Graduate School of Medicine Department of Physical Medicine & Rehabilitation

reha@med.tohoku.ac.jp022-717-7338

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026