An analysis of the function of lower gastrointestinal tract using Endoscopic pressure study integrated system (EPSIS)

An analysis of the function of lower gastrointestinal tract using Endoscopic pressure study integrated system (EPSIS) - An analysis of the function of lower gastrointestinal tract using Endoscopic pressure study integrated system (EPSIS)

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000044774

Enrollment

150

Registered

2021-07-06

Start date

2021-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

functional gastrointestinal disorders

Interventions

Carbon dioxide insufflation into the intestinal tract during colonoscopy for subjects undergoing colonoscopy (FGID patients) Carbon dioxide insufflation into the intestinal tract during colonoscopy fo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing colonoscopy at the implementing facility

Exclusion criteria

Exclusion criteria: Patients who are pregnant. Patients with serious underlying diseases (serious respiratory disease, cardiac failure, renal failure, hepatic failure). Patients who are considered ineligible by the investigator

Design outcomes

Primary

Measure	Time frame
At the time of maximum intestinal distension Intra-intestinal pressure (IIP) max Intra-intestinal pressure (IIP) max at the time of maximum intestinal distension Uphill pattern/flat pattern Intestinal pressure waveform slope Endoscopic findings at the time the maximum pressure was recorded Investigate trends in each section (small bowel, cecum to ascending colon, transverse colon, descending colon, sigmoid colon, rectum).	—

Measure

Time frame

At the time of maximum intestinal distension Intra-intestinal pressure (IIP) max Intra-intestinal pressure (IIP) max at the time of maximum intestinal distension Uphill pattern/flat pattern Intestinal pressure waveform slope Endoscopic findings at the time the maximum pressure was recorded Investigate trends in each section (small bowel, cecum to ascending colon, transverse colon, descending colon, sigmoid colon, rectum).

—

Secondary

Measure	Time frame
Association with factors outside the intestinal tract that may affect intestinal content Association with factors outside the intestinal tract that may affect the intestinal content: body size (height and weight BMI), history of abdominal surgery, inflammatory diseases of the abdomen, etc. Endoscopic findings: association with factors related to intestinal wall extension (e.g., scarring of the intestine) Intra-intestinal pressure changes when intestinal peristalsis is induced Changes in bowel pressure before and after administration of a test drug that has an effect on bowel peristalsis Changes in abdominal symptoms associated with pressurization (non-sedated patients) Assess the relationship between the degree of distress and the pressure at which distress was felt using the VAS scale	—

Measure

Time frame

Association with factors outside the intestinal tract that may affect intestinal content Association with factors outside the intestinal tract that may affect the intestinal content: body size (height and weight BMI), history of abdominal surgery, inflammatory diseases of the abdomen, etc. Endoscopic findings: association with factors related to intestinal wall extension (e.g., scarring of the intestine) Intra-intestinal pressure changes when intestinal peristalsis is induced Changes in bowel pressure before and after administration of a test drug that has an effect on bowel peristalsis Changes in abdominal symptoms associated with pressurization (non-sedated patients) Assess the relationship between the degree of distress and the pressure at which distress was felt using the VAS scale

—

Countries

Japan

Contacts

Public ContactAkiko Toshimori

Showa University Koto Toyosu Hospital Digestive disease center

akikotoshimori@med.showa-u.ac.jp0362046000

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026