Delayed contrast-enhanced computed tomography for assessment of myocardial injury after coronavirus disease 2019 (COVID-19) infection

Delayed contrast-enhanced computed tomography for assessment of myocardial injury after coronavirus disease 2019 (COVID-19) infection - Delayed contrast-enhanced computed tomography for assessment of myocardial injury after coronavirus disease 2019 (COVID-19) infection

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000044762

Enrollment

400

Registered

2021-07-05

Start date

2021-07-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronavirus disease 2019 (COVID-19) infection

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients 18 years of age or older are eligible. 2. Patients after recovery from coronavirus disease 2019 (COVID-19) infection are eligible. Diagnosis of COVID-19 requires at least 1 positive polymerase chain reaction result for SARS-CoV-2 in the nasopharyngeal swab or sputum. 3. Patients who are scheduled for coronary computed tomography angiography are eligible. 4. Patients who provided informed consent are eligible.

Exclusion criteria

Exclusion criteria: 1. Patients expected to live a year or less 2. Patients with insufficient image quality of delayed contrast-enhanced computed tomography 3. Patients who withdraw their consent 4. Patients who contact persons judge as ineligible for this study

Design outcomes

Primary

Measure	Time frame
Major adverse cardiovascular events (MACE: the composite of all-cause mortality, lethal ventricular arrhythmias [sustained ventricular tachycardia/ventricular fibrillation], myocardial infarction, and stroke), heart failure or unstable angina requiring hospitalization, and thromboembolic events after the delayed contrast-enhanced computed tomography examination.	—

Secondary

Measure	Time frame
The prespecified secondary outcomes of the study are as follows: 1. prevalence of coronary artery disease and myocardial injury assessed by contrast-enhanced computed tomography. 2. diagnostic value of delayed contrast-enhanced computed tomography for the assessment of myocardial injury in comparison with late gadolinium enhancement cardiovascular magnetic resonance 3. cross-sectional and longitudinal associations between myocardial injury, echocardiographic indices, and biomarkers. 4. incidence and predictors of all-cause death, MACE, MACE+.	—

Measure

Time frame

The prespecified secondary outcomes of the study are as follows: 1. prevalence of coronary artery disease and myocardial injury assessed by contrast-enhanced computed tomography. 2. diagnostic value of delayed contrast-enhanced computed tomography for the assessment of myocardial injury in comparison with late gadolinium enhancement cardiovascular magnetic resonance 3. cross-sectional and longitudinal associations between myocardial injury, echocardiographic indices, and biomarkers. 4. incidence and predictors of all-cause death, MACE, MACE+.

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Countries

Japan

Contacts

Public ContactTadao Aikawa

Hokkaido Cardiovascular Hospital Cardiology

tadao.aikawa@juntendo.ac.jp011-563-3911

Outcome results