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Study on the pathophysiology of epilepsy using a [18F]BCPP-EF PET tracer

Study on the pathophysiology of epilepsy using a [18F]BCPP-EF PET tracer - Microglia and mitochondria PET

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000044752
Enrollment
60
Registered
2021-07-04
Start date
2021-06-29
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epilepsy

Interventions

Sponsors

Department of Biofunctional Imaging, Hamamatsu University School of Medicine
Lead Sponsor
Hamamatsu Medical Photonics Foundation NHO, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders Hamamatsu Photonics
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Healthy participants aged 18 to 75 years 2. Individuals who have no history of psychiatric and neurological disease 3. Individuals who are consent to participate in this study 4. Patients with epilepsy (aged 18 to 75 years)

Exclusion criteria

Exclusion criteria: 1. Individuals who are suspected pregnant, pregnant or breast-feeding. 2. Individuals who have a history of claustrophobia. 3. Individuals who are considered unsuitable by doctors in charge. 4. Individuals with undergoing diabetes treatments who have the blood glucose level over 190mg/dl before PET examination. In other day, less than 190mg/dl is enable.

Design outcomes

Primary

MeasureTime frame
Elucidation of pathophysiology of epilepsy by examining the binding of [18F]BCPP-EF and [11C]DPA713PET tracers between epilepsy and normal control group.

Secondary

MeasureTime frame
Correlation of the PET tracer binding with clinical information, electroencephalogram, neuroimaging examinations and psychological date.

Countries

Japan

Contacts

Public ContactYasuomi Ouchi

Hamamatsu University School of Medicine Department of Biofunctional Imaging

ouchi@hama-med.ac.jp053-435-2466

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026