Post-ESD coagulation syndrome
Conditions
Interventions
Add a diclofenac sodium sup. (50mg) immediately after colorectal ESD once.
Perform a rectal examination immediately after colorectal ESD.
Sponsors
Omori Red Cross Hospital, Department of Gastroenterology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients who are going to receive colorectal ESD for the neoplasm 20 mm in size or larger, except for the tumor located in the Rb (rectum below the peritoneal reflection). 2) Patients who are 20 years old or older and 85 years old or younger.
Exclusion criteria
Exclusion criteria: 1) major organ failure (Liver disease; Child-Pugh classification C, Renal disease; stage 4 or higher, Heart failure; NYHA classification 3 or higher). 2) Performance Status(ECOG) 3 or 4. 3) Patients who use steroids or NSAIDs regularly. 4) Patients with Visual analog scale (VAS) >20mm, WBC > 10000, or body temperature > 37.0 at the time before ESD. 5) Patients who are contraindicant to NSAIDs use. 6) Patients who are going to have ESD or EMR for multiple lesions simultaneously. 7) The cases of intraoperative perforation. 8) The patients who are judged by attending doctors as not suitable for this trial. If systolic blood pressure is under 70 mmHg, diclofenac sodium cannot be given to the patient.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incident rate of PECS. | — |
Countries
Japan
Contacts
Public ContactNaoya Okada
Omori Red Cross Hospital Department of gastroenterology
Outcome results
None listed