Examination of the relationship between biomarkers in nasal discharge during initial wheezing and the onset of asthma in early childhood

Examination of the relationship between biomarkers in nasal discharge during initial wheezing and the onset of asthma in early childhood - Examination of the relationship between biomarkers in nasal discharge during initial wheezing and the onset of asthma in early childhood

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000044655

Enrollment

148

Registered

2021-06-26

Start date

2021-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchial asthma

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Infants under 2 years old who were hospitalized for lower respiratory tract infection and wheezing for the first time after birth Children who have consented to participate in this study from their substitutes

Exclusion criteria

Exclusion criteria: Preterm infants (less than 37 weeks) Children who required respiratory management during the newborn period, children with chronic lung disease Children with a history of autoimmune diseases or metabolic diseases Children who received treatment by steroids (inhalation, nasal drops, systemic administration) before sample collection (within 24 hours) Other children who the researcher deems inappropriate for participating in this study

Design outcomes

Primary

Measure	Time frame
Differences in nasal discharge biomarkers tested at the time of screening between children in the IgE-related asthma group, non-IgE-related asthma group, and non-asthma group.	—

Countries

Japan

Contacts

Public ContactFumitaka Takayanagi

Dokkyo Medical University Hospital Pediatrics

fumi_fena@yahoo.co.jp0282-86-1111

Outcome results