Multicenter retrospective observational study to compare Prognosis of Patients with T1 Colorectal cancer with high Risk of lymph node metastasis after endoscopic treatment between additional surgery and observatioN (the POPCORN Study)

Multicenter retrospective observational study to compare Prognosis of Patients with T1 Colorectal cancer with high Risk of lymph node metastasis after endoscopic treatment between additional surgery and observatioN (the POPCORN Study) - Multicenter retrospective observational study to compare Prognosis of Patients with T1 Colorectal cancer with high Risk of lymph node metastasis after endoscopic treatment between additional surgery and observatioN (the POPCORN Study)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000044644

Enrollment

200

Registered

2021-06-24

Start date

2021-06-17

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who met one or more of the following criteria after ESD for pT1b colorectal cancer 1) SM invasion depth of more than 1000 um 2) positive vascular invasion 3) poorly differentiated adenocarcinoma, signet ring cell carcinoma, mucinous carcinoma 4) high grade tumor budding (Grade 2/ 3) at the SM invasive part 5) positive vertical margin

Exclusion criteria

Exclusion criteria: 1) Patients who underwent EMR (Endoscopic mucosal resection) instead of ESD 2) Patients who is judged to be ineligible to participate in the study by the research principal doctor

Design outcomes

Primary

Measure	Time frame
Overall survival	—

Secondary

Measure	Time frame
Relapse-free survival, Morbidity rate and rate of lymph node metastasis in the additional surgery group	—

Countries

Japan

Contacts

Public ContactYosuke Atsumi

Yokohama City University Department of Surgery

yosuke21@yokohama-cu.ac.jp045-787-2800

Outcome results