Optimal Tentative Abdominal Closure for Open Abdomen

Optimal Tentative Abdominal Closure for Open Abdomen - OPTITAC trial

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000044619

Enrollment

250

Registered

2021-06-23

Start date

2021-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who underwent open abdomen

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who underwent open abdomen between January 2010 and March 2021

Exclusion criteria

Exclusion criteria: Patients who died within 48 h after the initial surgery of open abdomen Patients who had DNAR order within 48 h after the initial surgery of open abdomen Patients with ventral hernia that was diagnosed before open abdomen and fascia could not be closed due to the hernia

Design outcomes

Primary

Measure	Time frame
Primary fascia closure	—

Secondary

Measure	Time frame
Days to primary fascia closure, adverse events (enteroatmospheric fistula, anastomotic leakage, wound dehiscence, ventral hernia, surgical site infection, any other fistula), 28day mortality, in-hospital mortality, ICU free days to day28, ventilator free days to day28, RRT free days to day28, hospital free days to day28, SOFA and APACHEII score at day7 after initiating open abdomen, re-admission within 30 days after discharge, disposition at discharge	—

Measure

Time frame

Days to primary fascia closure, adverse events (enteroatmospheric fistula, anastomotic leakage, wound dehiscence, ventral hernia, surgical site infection, any other fistula), 28day mortality, in-hospital mortality, ICU free days to day28, ventilator free days to day28, RRT free days to day28, hospital free days to day28, SOFA and APACHEII score at day7 after initiating open abdomen, re-admission within 30 days after discharge, disposition at discharge

—

Countries

Japan

Contacts

Public ContactRyo Yamamoto

Keio University School of Medicine Department of Emergency and Critical Care Medicine

ryoyamamoto@keio.jp03-3225-1323

Outcome results