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Efficacy and evaluation of the application of mixed reality rehabilitation training coupled with artificial intelligence analysis software for upper limb rehabilitation in stroke patients

Efficacy and evaluation of the application of mixed reality rehabilitation training coupled with artificial intelligence analysis software for upper limb rehabilitation in stroke patients - Efficacy and evaluation of the application of mixed reality rehabilitation training coupled with artificial intelligence analysis software for upper limb rehabilitation in stroke patients

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000044590
Enrollment
30
Registered
2022-05-15
Start date
2021-12-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Experiment on rehabilitation targeting stroke patients using mixed reality rehabilitation

Interventions

rehabilitation without mixed reality rehabilitation Healthy individuals who does not require rehabilitation will be going through the same length of process as others

Sponsors

Ministry of science and technology, Republic of China MOST 105-2321-B-214-001
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: patient age between 20 to 75 years, first onset of stroke over 3 months. Brunnstrom stage higher than 3, having a diagnosis with stroke and confirmed with Computed tomography or Magnetic Resonance Imaging scans, being able to understand instructions, Mini-Mental State Examination score higher than 18 and, no other neurological disorders as comorbid.

Exclusion criteria

Exclusion criteria: participated in other rehabilitation related or clinical trials within 3 months of the experiment, having sensory apraxia, having severe impairments in vision or visual perception such as hemi-neglect, receiving warfarin or VitK antagonist treatment, having high risk of epilepsy, failure to cooperate with the researcher to execute mixed reality rehabilitation activities and refusing to take the blood test.

Design outcomes

Primary

MeasureTime frame
Results shown that upper limb function (FMA-UE), biomarkers correlated to oxidative stress (HO-1 and 8-OHdG), and BDNF have significant improvement after mixed reality rehabilitation trainings.

Secondary

MeasureTime frame
Although the change of serum molecular in mixed reality rehabilitation group did not reached significance compared to the control group. It is also suggests that the motor recovery was associated with the increase of HO-1 and decrease of 8-OHdG.

Countries

Asia(except Japan)

Contacts

Public ContactPing-Chia Li

I-Shou Univeristy Department of Occupational Therapy

pingchiali@gmail.com886761511007513

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026