healthy volunteer
Conditions
Interventions
None listed
Sponsors
Chiba university
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Age: 20 years and over 2) Agreement to a doctor's interview regarding health condition. 3) Systolic blood pressure is 90-160 mmHg and diastolic blood pressure is 100 mmHg or less 4) Weight: men 45 kg or more, women 40 kg or more 5) After receiving sufficient explanation for participation in this study, written consent by free will have been obtained with sufficient understanding
Exclusion criteria
Exclusion criteria: 1) There is a disease that requires treatment, or the patient is under examination due to suspicion of the disease. 2) Have a history of blood disorders 3) History of blood transfusion or history of organ transplantation 4) Pregnant or within 1 year of delivery 5) History of the following infectious diseases (A) Malaria, Toxoplasma (B) Tuberculosis within 5 years after healing (C) Sexually transmitted diseases within 1 year after healing (D) Dengue fever within 1 month after healing (E) Onset of erythema infectiosum in the person within 6 months after healing or onset in the family within 1 month 6) Anyone judged inappropriate by the doctor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ex vivo cell proliferation assays are performed on peripheral blood mononuclear cells of healthy volunteers. | — |
Secondary
| Measure | Time frame |
|---|---|
| If necessary, using peripheral blood mononuclear cell samples treated with drugs, changes in gene expression, histone modification and open chromatin regions will be assesed by RNA-seq, ChIP-seq and ATAC-seq. | — |
Countries
Japan
Contacts
Public ContactYoshiro Hirasaki
Graduate School of Medicine, Chiba university Department of Japanese-Oriental (Kampo) Medicine
Outcome results
None listed