ischemic stroke
Conditions
Interventions
Intervention group: a manual blood pressure cuff will be placed around the lower leg or thigh of the unaffected side, and blood pressure will be measured while detecting the dorsalis pedis artery usin
however, if the patient cannot tolerate this, the cuff pressure may be 180 mmHg. This procedure will be performed once daily after enrollment, for a minimum of 3 days and a maximum of 7 days. Discomfo
Sponsors
Tokyo Women's Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1 Written informed consent [patient or legal representative] 2 Male and Female patients [20<= age <= 90 years] 3 Diagnosed acute ischemic stroke by performing brain MRI and/or CT 4 Within 48 hours after stroke onset 5 NIHSS scores range from 5-20 at registration 6 Systolic blood pressure of upper and lower limbs is tolerable and systolic blood pressure is less than 180 mmHg
Exclusion criteria
Exclusion criteria: 1 mRS is more than 2 before stroke onset 2 rt-PA and/or EVT treated AIS after registration 3 Within 12 hours after rt-PA administration or EVT 4 History of PAD 5 Systric blood pressure is more than 180 mmHg 6 Patients deemed unsuitable as subjects by the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| good functional outcome at 3-months after stroke onset, assessed by the mRS, with a target mRS score of 0-1 in the mild group, 0-2 in the moderate group, and 0-3 in the severe group. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) the proportion of patients with a good functional outcome (assessed by the mRS) in each group at 3 months after stroke onset; 2) the change in NIHSS scores from before RIC to after RIC; 3) the incidence of major adverse cardiovascular events, aspiration pneumonia, and all-cause mortality after stroke onset; 4) the frequency of adverse RIC-related events; and 5) the proportion of patients with a mRS score of 0-1. | — |
Countries
Japan
Contacts
Public ContactKentaro Ishizuka
Tokyo Women's Medical University department of neurology
Outcome results
None listed