A study for effects on body surface temperature and feeling of "Ninnikushoga" intake under cool conditions in healthy adult female who are concerned about cold.

A study for effects on body surface temperature and feeling of "Ninnikushoga" intake under cool conditions in healthy adult female who are concerned about cold. - A study for effects on body surface temperature and feeling of "Ninnikushoga" intake under cool conditions in healthy adult female who are concerned about cold.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000044513

Enrollment

Registered

2021-06-13

Start date

2021-06-14

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adult

Interventions

Intake of test food (single ingestion) - washing out (a day or more) - intake of placebo (single ingestion) Intake of placebo (single ingestion) - washing out (a day or more) - intake of test food (si

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: (1)Healthy females from 20 to 64 years of age (2)Subjects who are aware of getting cold of fingers under air conditioner working (3)Subjects who live an ordered life (4)Subjects who drop body surface temperature under cool conditions on preliminary examination

Exclusion criteria

Exclusion criteria: (1)Subjects who have been diagnosed underlying disease accompanied with angiopathy (e.g. arteriosclerosis obliterans, arteritis obliterans, collagen disease and diabetes, etc.) (2)Subjects who constantly take medicines affecting the skin surface temperature(e.g. warfarin) (3)Subjects who eat food for specified health or health food affecting the skin surface temperature(e.g. healthy food including garlic or ginger) at least once a week (4)Subjects having food allergy (5)Subjects who are smokers or have smoked within the past 3 months (6)Subjects who have a scar affecting the skin surface temperature and autonomic function on fingers, palms, toes and insteps (7)Subjects who have worked shifts day and night or are planned to work shifts day and night from a month before obtaining the consent for this study to the date of the completion this study (8)Subjects who have gone abroad or are planned to go abroad from a month before obtaining the consent for this study to the date of the completion this study (9)Subjects who have participated in other clinical study within the last one month prior to the current study or are planned to participate in other clinical study after informed consent for the current study (10)Subjects who intend to become pregnant or lactating during the study (11)Subjects having a disease requiring treatment or taking medicines (12)Subjects having a history of serious diseases (13)Subjects who are judged as unsuitable for the study based on the results of lifestyle questionnaire (14)Subjects who are not judged as healthy based on the results of clinical and physical examination on preliminary examination (15)Subjects who are judged as unsuitable for the study based on the results of clinical and physical examination on preliminary examination

Design outcomes

Primary

Measure	Time frame
Area under the curve of body surface temperature	—

Secondary

Measure	Time frame
Body surface temperature Autonomic function Subjective symptoms questionnaire	—

Countries

Japan

Contacts

Public ContactYoshimi Bansho

EP Mediate Co., Ltd. Development Business Headquarters, TTC Center, Trial Planning Department

bansho189@eps.co.jp03-5657-4983

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026

A study for effects on body surface temperature and feeling of &quot;Ninnikushoga&quot; intake under cool conditions in healthy adult female who are concerned about cold.